Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors
Isothiocyanates induce cell cycle arrest
S-(+)-Rolipram suppresses LPS-induced TNFα expression from human monocyte through inhibiting PDE4 with IC50 about 2 μM
ClH/c1-23-19-8-7-15(13-20(19)24-2)10-12-25-18-6-4-3-5-17(18)21-11-9-16(22)14-21
PDE-9 inhibitor is useful for neurodegenerative diseases
Estradiol benzoate 3258 analog Exploiting an allosteric binding siteEstradiol Benzoate ( Estradiol 3 benzoate), a prodrug of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability. Product information CAS Number: 50 50 0 Molecular Weight: 376. 49 Formula: C25H28O3 Synonym: Estradiol 3 benzoate 17 Estradiol 3 benzoate Chemical Name: (1S,3aS,3bR,9bS,11aS) 3a,3b,9b trihydrogenio 1 hydroxy 11a methyl 1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH